BDBM585773 US11530229, Compound 1

SMILES Cc1cc(nc(n1)C1CC1)C(=O)Nc1cccc(c1)[C@@]1(Cc2nncn2C)C[C@@H](C1)C#N

InChI Key InChIKey=AVHROJXYFUWPQG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 585773   

LigandPNGBDBM585773(US11530229, Compound 1)
Affinity DataIC50: 3.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM585773(US11530229, Compound 1)
Affinity DataIC50: 3nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent

LigandPNGBDBM585773(US11530229, Compound 1)
Affinity DataIC50: 1.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent