BDBM585709 8-chloro-1-(2,6-dichlorophenyl)-5- (2-(2-(2-(2- hydroxyethoxy)ethoxy)ethoxy)eth- oxy)-2-methyl-1,6-naphthyridin- 4(1H)-one::US11530213, Example 30

SMILES Cc1cc(=O)c2c(OCCOCCOCCOCCO)ncc(Cl)c2n1-c1c(Cl)cccc1Cl

InChI Key InChIKey=LBCVNBYMBREQQW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585709   

LigandPNGBDBM585709(US11530213, Example 30 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 25nMAssay Description:Quattro is controlled using IonWorks v2 software to perform the following steps:a. Add 3.5 ul cells plus 3.5 ul external buffer to wells of Quattro P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
Go to US Patent

TargetG protein-activated inward rectifier potassium channel 4(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM585709(US11530213, Example 30 | 8-chloro-1-(2,6-dichlorop...)
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human GIRK1/4 channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed