BDBM583573 US11524959, Compound 465.::US11524959, Compound 483.

SMILES COc1cc(cc2nc(-c3cc4ccc(nc4n3CC3CC3)-c3cccc4[nH]c(=O)ccc34)n(C)c12)C(=O)N1CC2CCC1[C@@H]2N

InChI Key InChIKey=WPGXXNFPQSXEDI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 583573   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM583573(US11524959, Compound 483. | US11524959, Compound 4...)
Affinity DataIC50: 16nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a 10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM583573(US11524959, Compound 483. | US11524959, Compound 4...)
Affinity DataIC50: 28nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a 10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent