BDBM583231 5-(2-{5-[(1R,4R,7R)-7-amino-2- azabicyclo[2.2.1]heptane-2- carbonyl]-7-methoxy-1-methyl-1H- 1,3-benzodiazol-2-yl}-1- (cyclopropylmethyl)-1H-indol-6-yl)- 2,3-dihydro-1H-isoindol-1-one::US11524959, Compound 123.

SMILES COc1cc(cc2nc(-c3cc4ccc(cc4n3CC3CC3)-c3ccc4C(=O)NCc4c3)n(C)c12)C(=O)N1CC2CCC1[C@@H]2N

InChI Key InChIKey=WRRISOAPWUFJDO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 583231   

TargetProtein-arginine deiminase type-4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM583231(US11524959, Compound 123. | 5-(2-{5-[(1R,4R,7R)-7-...)
Affinity DataIC50: 18nMAssay Description:Compounds were solubilized in 100% DMSO to achieve a 10 mM compound concentration. Compound stock solutions were stored at RT. A series of dilutions ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
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