BDBM582023 US11518754, Compound (S)-3

SMILES Cc1cnccc1CN1C[C@@H](CC1=O)c1cc(F)c(F)c(F)c1

InChI Key InChIKey=RFSDYRVOGWHOFT-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 582023   

TargetSynaptic vesicle glycoprotein 2A(Rat)
Yale University

US Patent
LigandPNGBDBM582023(US11518754, Compound (S)-3)
Affinity DataIC50: 75.6nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent

TargetSynaptic vesicle glycoprotein 2A(Rat)
Yale University

US Patent
LigandPNGBDBM582023(US11518754, Compound (S)-3)
Affinity DataKi:  12.5nMAssay Description:For competition binding experiments, 0.5 mg of the rat brain homogenates in 800 μL of binding buffer (2 mM MgCl2 in 50 mM Tris*HCl, pH=7.4) were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent