BDBM581307 (2R)-2-[(4S)-4-carboxy-4-[(5- {[(2,4-diamino-6-oxo-1,6- dihydropyrimidin-5- yl)carbamoyl]amino}pyridin-2- yl)formamido]butanamido]- pentanedioic acid::US11504368, Example 25

SMILES Nc1nc(N)c(NC(=O)Nc2ccc(nc2)C(=O)N[C@@H](CCC(=O)N[C@H](CCC(O)=O)C(O)=O)C(O)=O)c(=O)[nH]1

InChI Key InChIKey=JKGSWFFLWSOSSE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581307   

TargetBifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial(Human)
Thomas Helledays Stiftelse FÖR Medicinsk Forskning

US Patent
LigandPNGBDBM581307(US11504368, Example 25 | (2R)-2-[(4S)-4-carboxy-4-...)
Affinity DataIC50: 30nMAssay Description:To determine the IC50 value of a compound, an 11-concentration dose-response curve with 3-fold difference in concentration between assay points was g...More data for this Ligand-Target Pair
In DepthDetails
US Patent