BDBM58106 6-(1,3-dihydrophenanthr[9,10-d]imidazol-2-ylidene)cyclohexa-2,4-dien-1-one::6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene)-1-cyclohexa-2,4-dienone::6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene)cyclohexa-2,4-dien-1-one::MLS000758520::SMR000528957::cid_5384447

SMILES Oc1ccccc1-c1nc2c([nH]1)c1ccccc1c1ccccc21

InChI Key InChIKey=USJRSBYEUBALIV-UHFFFAOYSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 58106   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataEC50:  4.11E+3nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in presence of GSH and tw...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of full length recombinant human His-tagged IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant human IDO1 expressed in bacterial expression system using L-Tryptophan as substrate after 25 mins in absence of GSH and pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2019
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 assessed as reduction in N-formylkynurenine formation using L-tryptophan as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM58106(6-(1,3-dihydrophenanthro[9,10-d]imidazol-2-ylidene...)
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed