BDBM579247 US11479560, Title KM-4-214-1::US11479560, Title KM-4-267-3::US11479560, Title KM-4-287::US11479560, Title ww5-190

SMILES Cc1ccc(CC(CNC(=O)CO)n2c3ccccc3n(Cc3ccc(C)cc3)c2=N)cc1

InChI Key InChIKey=CXVSRMKXOCVSJS-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 579247   

TargetOrexin receptor type 2(Human)
University of Texas System

US Patent
LigandPNGBDBM579247(US11479560, Title ww5-190 | US11479560, Title KM-4...)
Affinity DataEC50:  1.50E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
University of Texas System

US Patent
LigandPNGBDBM579247(US11479560, Title ww5-190 | US11479560, Title KM-4...)
Affinity DataEC50:  1.50E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
University of Texas System

US Patent
LigandPNGBDBM579247(US11479560, Title ww5-190 | US11479560, Title KM-4...)
Affinity DataEC50:  1.50E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent

TargetOrexin receptor type 2(Human)
University of Texas System

US Patent
LigandPNGBDBM579247(US11479560, Title ww5-190 | US11479560, Title KM-4...)
Affinity DataEC50:  1.50E+3nMAssay Description:HEK293 cells stably expressing OX2R are transfected with Gq alpha construct (6.4 ug per 10 cm dish) using Lipofectamine 3000 (ThermoFisher). 24 hours...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2022
Entry Details
Go to US Patent