BDBM577466 (R)-(((3-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-1,1-difluoropropan-2-yl)oxy)methyl)phosphonic Acid (Compound 66)::US11472826, # 66

SMILES Nc1ncnc2c(C[C@@H](OCP(O)(O)=O)C(F)F)cnn12

InChI Key InChIKey=TXHPECJQNGRFJO-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577466   

TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577466(US11472826, # 66 | (R)-(((3-(4-aminopyrazolo[1,5-a...)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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