BDBM577427 (((1-(4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-7-yl)propan-2-yl)oxy)methyl)phosphonic Acid ::US11472826, # 13

SMILES CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cc1cnn2c(N)ncnc12)OCOC(=O)OC(C)C

InChI Key InChIKey=UBPVWRLHTDUIAQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577427   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577427(US11472826, # 13 | (((1-(4-oxo-3,4-dihydropyrrolo[...)
Affinity DataEC50: <2.00E+4nMAssay Description:24 hours prior to infection, CEM human T lymphoblast cells (ATCC, Manassas, Va.) were plated in assay media (MEM supplemented with 10% FBS, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577427(US11472826, # 13 | (((1-(4-oxo-3,4-dihydropyrrolo[...)
Affinity DataEC50: >1.00E+5nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent