BDBM577425 (1-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)propan-2-yloxy)methylphosphonic Acid ::US11472826, # 11

SMILES CC(C)OC(=O)OCOP(=O)(CO[C@H](C)Cc1ccc2c(N)ncnn12)OCOC(=O)OC(C)C

InChI Key InChIKey=FYTDMIUKGUPUID-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 577425   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577425(US11472826, # 11 | (1-(4-aminopyrazolo[1,5-a][1,3,...)
Affinity DataEC50: <2.00E+4nMAssay Description:24 hours prior to infection, CEM human T lymphoblast cells (ATCC, Manassas, Va.) were plated in assay media (MEM supplemented with 10% FBS, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577425(US11472826, # 11 | (1-(4-aminopyrazolo[1,5-a][1,3,...)
Affinity DataEC50: <1.00E+3nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent