BDBM577424 (1-(4-aminopyrazolo[1,5-a][1,3,5]triazin-8-yl)-3-fluoropropan-2-yloxy)methylphosphonic Acid ::US11472826, # 10::US11472826, # 10c::US11472826, # 10d

SMILES CCOP(=O)(COC(CF)Cc1cnn2c(N)ncnc12)OCC

InChI Key InChIKey=LDPTUMZSBIVKLF-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577424   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577424(US11472826, # 10 | US11472826, # 10c | US11472826,...)
Affinity DataEC50: <2.00E+4nMAssay Description:24 hours prior to infection, CEM human T lymphoblast cells (ATCC, Manassas, Va.) were plated in assay media (MEM supplemented with 10% FBS, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577424(US11472826, # 10 | US11472826, # 10c | US11472826,...)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577424(US11472826, # 10 | US11472826, # 10c | US11472826,...)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

TargetLarge envelope protein(HBV-D)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577424(US11472826, # 10 | US11472826, # 10c | US11472826,...)
Affinity DataEC50:  5.50E+3nMAssay Description:Determination of 50% inhibitory concentration (EC50) of compounds in HCV replicon cells were performed by the following procedure. On the first day, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent