BDBM577419 (R)-(((1-(4-aminoimidazo[2,1-f][1,2,4]triazin-7-yl)propan-2-yl)oxy)methyl)phosphonic Acid ::US11472826, # 5

SMILES CCOP(=O)(CO[C@H](C)Cc1cnc2c(N)ncnn12)OCC

InChI Key InChIKey=MZLSHPWMVPAFGV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577419   

TargetEnvelope glycoprotein gp160(Human immunodeficiency virus type 1)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM577419(US11472826, # 5 | (R)-(((1-(4-aminoimidazo[2,1-f][...)
Affinity DataEC50: <2.00E+4nMAssay Description:24 hours prior to infection, CEM human T lymphoblast cells (ATCC, Manassas, Va.) were plated in assay media (MEM supplemented with 10% FBS, 1% penici...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent