BDBM577337 2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-N-((4-methylpyridin-2-yl)methyl)-2-phenylpropanamide::US11472811, Example 110

SMILES Cc1ccnc(CNC(=O)C(C)(c2ccccc2)n2ncc3c2nc(N)n2nc(nc32)-c2ccco2)c1

InChI Key InChIKey=JFKWTLTUEBNDPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577337   

TargetAdenosine deaminase(Human)
Beigene

US Patent
LigandPNGBDBM577337(US11472811, Example 110 | 2-(5-amino-2-(furan-2-yl...)
Affinity DataIC50: 2.40nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent