BDBM577259 2-(5-amino-2-(furan-2-yl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-2-phenyl-N-(((S)-tetrahydrofuran-2-yl)methyl)propanamide::US11472811, Example 51

SMILES CC(C(=O)NC[C@@H]1CCCO1)(c1ccccc1)n1ncc2c1nc(N)n1nc(nc21)-c1ccco1

InChI Key InChIKey=NESYUEDPVLLQNE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 577259   

TargetAdenosine deaminase(Human)
Beigene

US Patent
LigandPNGBDBM577259(US11472811, Example 51 | 2-(5-amino-2-(furan-2-yl)...)
Affinity DataIC50: 2.70nMAssay Description:HEK293-A2AR-luc2p/CRE/Hygro cells were seeded at a density of 5,000 cells/well in DMEM with 1% FBS and 1 U/mL adenosine deaminase (ADA) (Sigma). Afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
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