BDBM577169 10-(4-Chloro-2-methylphenyl)-8-(pyrimidin-2-yl)-7,8-dihydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one,trifluoroacetate salt::US11472805, Example 73

SMILES Cc1cc(Cl)ccc1-c1c2C(=O)N(CCn2c2cccnc12)c1ncccn1

InChI Key InChIKey=TVPGHEMRNSSWKT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577169   

LigandPNGBDBM577169(US11472805, Example 73 | 10-(4-Chloro-2-methylphen...)
Affinity DataIC50: 7.66nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

LigandPNGBDBM577169(US11472805, Example 73 | 10-(4-Chloro-2-methylphen...)
Affinity DataIC50: 25.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

LigandPNGBDBM577169(US11472805, Example 73 | 10-(4-Chloro-2-methylphen...)
Affinity DataIC50: 122nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent

LigandPNGBDBM577169(US11472805, Example 73 | 10-(4-Chloro-2-methylphen...)
Affinity DataIC50: 700nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
Go to US Patent