BDBM577166 4-(8-Cyclopropyl-9-oxo-8,9-dihydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-10-yl)benzonitrile::US11472805, Example 70

SMILES O=c1n(ccn2c3cccnc3c(-c3ccc(cc3)C#N)c12)C1CC1

InChI Key InChIKey=LQSTXUKGXUCNPL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577166   

LigandPNGBDBM577166(US11472805, Example 70 | 4-(8-Cyclopropyl-9-oxo-8,...)
Affinity DataIC50: 2.80nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577166(US11472805, Example 70 | 4-(8-Cyclopropyl-9-oxo-8,...)
Affinity DataIC50: 2.67nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577166(US11472805, Example 70 | 4-(8-Cyclopropyl-9-oxo-8,...)
Affinity DataIC50: 8.55nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577166(US11472805, Example 70 | 4-(8-Cyclopropyl-9-oxo-8,...)
Affinity DataIC50: 108nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent