BDBM577136 8-Cyclopropyl-10-(3-fluorophenyl)-7,8-dihydropyrido[2',3':4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one::US11472805, Example 41

SMILES Fc1cccc(c1)-c1c2C(=O)N(CCn2c2cccnc12)C1CC1

InChI Key InChIKey=CITPCSPDQMOFRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577136   

LigandPNGBDBM577136(US11472805, Example 41 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 1.26nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577136(US11472805, Example 41 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 2.38nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577136(US11472805, Example 41 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 9.22nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577136(US11472805, Example 41 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent