BDBM577090 10-(4-Chloro-3-fluorophenyl)-8-cyclopropyl-7,8-dihydropyrazino[1′,2′: 1,5]pyrrolo[3,2-d]pyrimidin-9(6H)-one (7::US11472805, Example 7

SMILES Fc1cc(ccc1Cl)-c1c2C(=O)N(CCn2c2cncnc12)C1CC1

InChI Key InChIKey=SEAKUVPPGRMOIJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 577090   

LigandPNGBDBM577090(US11472805, Example 7 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 14.3nMAssay Description:The PDE4A3, PDE4B1, PDE4C1 and PDE4D3 assays use the Scintillation Proximity Assay (SPA) technology to measure the inhibition of human recombinant PD...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577090(US11472805, Example 7 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 2.53nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577090(US11472805, Example 7 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 71.4nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577090(US11472805, Example 7 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 159nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent