BDBM577049 US11472802, Example 55

SMILES CC(C)n1nc(-c2noc(C3CC3)c2-c2cn(C)cn2)c2c(N)ncc(Cl)c12

InChI Key InChIKey=LOCRUBFQZRFBTM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 577049   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Array Biopharma

US Patent
LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50: 0.200nMAssay Description:The potency of compounds inhibiting several different RET kinase forms (Wild Type, V804M, M918T, G810R, & G810S) were determined using CisBio's H...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50: 2.30nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM577049(US11472802, Example 55)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent