BDBM576377 N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]heptan-2-yl]-5-methoxy-furan-2-carboxamide::WO2022112207, Example 8

SMILES COc1ccc(o1)C(=O)NC1CC2(C1)CC(C2)c1nc2cc(Cl)ccc2o1

InChI Key InChIKey=NWLYYMYIJSNWPW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576377   

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576377(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 7.97E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576377(N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]hepta...)
Affinity DataIC50: 5.84E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207