BDBM576373 4-bromo-N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3.3]heptan-2-yl]furan-2-carboxamide::WO2022112207, Example 4

SMILES Clc1ccc2oc(nc2c1)C1CC2(CC(C2)NC(=O)c2cc(Br)co2)C1

InChI Key InChIKey=PVEKRQDTCRRAKB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 576373   

TargetLarge envelope protein(HBV-D)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576373(4-bromo-N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3...)
Affinity DataIC50: 5.57E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207

TargetExternal core antigen(HBVgbn)
F. Hoffmann-La Roche

WIPO
LigandPNGBDBM576373(4-bromo-N-[6-(5-chloro-1,3-benzoxazol-2-yl)spiro[3...)
Affinity DataIC50: 2.94E+3nMAssay Description:Detailed procedures regarding primary human hepatocyte (PHH) HBV natural infection assay are described as below. One tube of frozen PHH (10 million c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022112207