BDBM576253 WO2022109580, Example 14

SMILES CO[C@@]1(CCOC1)c1cc(OCC2COC2)cc(n1)-n1nc(C)c2cnc(NC(N)=O)cc12

InChI Key InChIKey=NGACWBKLQAMOJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 576253   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-871](Human)
Janssen Pharmaceutica

WIPO
LigandPNGBDBM576253(WO2022109580, Example 14)
Affinity DataIC50: 4nMAssay Description:The probe displacement assay is conducted as follows: In a 384-well plate, test compound along with recombinantly expressed His-tagged protein corres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2022
Entry Details
WIPO WO2022109580