BDBM575685 US11464802, Compound 49

SMILES C[C@H](N1CCC(F)(F)[C@H](C)C1)c1cc2C(=O)N(Cc2c(n1)C1CC1)c1cccc(c1)C1(Cc2nncn2C)COC1

InChI Key InChIKey=OISJDXXQZVMYHU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575685   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics

US Patent

LigandBDBM575685(US11464802, Compound 49)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/11/2022
Entry Details
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