BDBM575669 US11464802, Compound 32

SMILES C[C@@H]1CN(Cc2cc(nc(c2)C(=O)Nc2cccc(c2)C2(Cc3nncn3C)COC2)C2CC2)CCC1(F)F

InChI Key InChIKey=BVFZUAYLPACQET-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575669   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics

US Patent

LigandBDBM575669(US11464802, Compound 32)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/11/2022
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL