BDBM575659 US11464802, Compound 22

SMILES C[C@H]1C[C@H](CO)CN(Cc2cc3C(=O)N(Cc3c(c2)C(F)(F)F)c2cccc(c2)C2(Cc3nncn3C)COC2)C1

InChI Key InChIKey=JTZCNIIHMONJQZ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575659   

TargetIsoform Truncated 1 of E3 ubiquitin-protein ligase CBL-B [36-427] (Human)
Nurix Therapeutics

US Patent

LigandBDBM575659(US11464802, Compound 22)Copy SMILESCopy InChI

Affinity DataIC50: 1nMAssay Description:Fluorescently-labeled inhibitor probe was synthesized and tagged with BODIPY FL (Example 46). Cbl-b displacement assays were performed in a 384-well ...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/11/2022
Entry Details
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