BDBM575655 (S)-(6-((2-amino-3-chloropyridin-4-yl)thio)- 3-(5-amino-5,7-dihydrospiro-[cyclopenta[b] pyridine-6,4'-piperidin]-1'-yl) pyrazin-2-yl)methanol::US11459340, Compound 37
SMILES N[C@@H]1c2cccnc2CC11CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO
InChI Key InChIKey=ZMBQXYFCZWOIGG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 575655
Affinity DataIC50: 0.600nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair