BDBM575655 (S)-(6-((2-amino-3-chloropyridin-4-yl)thio)- 3-(5-amino-5,7-dihydrospiro-[cyclopenta[b] pyridine-6,4'-piperidin]-1'-yl) pyrazin-2-yl)methanol::US11459340, Compound 37

SMILES N[C@@H]1c2cccnc2CC11CCN(CC1)c1ncc(Sc2ccnc(N)c2Cl)nc1CO

InChI Key InChIKey=ZMBQXYFCZWOIGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 575655   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Nikang Therapeutics

US Patent
LigandPNGBDBM575655(US11459340, Compound 37 | (S)-(6-((2-amino-3-chlor...)
Affinity DataIC50: 0.600nMAssay Description:SHP2 possesses two N-terminal Src homology 2 (SH2) domains, a central protein-tyrosine phosphatase (PTP) domain, and C-terminal tail. At the basal st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
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