BDBM575082 US11459321, Example 27

SMILES COc1cc(Cc2cnc(s2)N2CCc3ccc(cc3C2)-n2cc(C)nc2C)ccc1-n1cccn1

InChI Key InChIKey=IZPJLSIEBBZOND-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 575082   

LigandPNGBDBM575082(US11459321, Example 27)
Affinity DataIC50: 345nMAssay Description:To assess their antiviral activity, some compounds were tested against human cytomegalovirus (HCMV) in vitro. Human MRCS cells were grown to confluen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent

TargetNeuraminidase(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Evrys Bio

US Patent
LigandPNGBDBM575082(US11459321, Example 27)
Affinity DataIC50: 2.23E+3nMAssay Description:To assess their antiviral activity, some compounds were tested against murine adapted human influenza (PR8) in vitro. Canine MDCK cells were grown to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2022
Entry Details
Go to US Patent