BDBM574486 US11458149, Compound I-39

SMILES NC(=O)\C=C\c1cc(Oc2cccc(c2)C(F)(F)F)cc2ncccc12

InChI Key InChIKey=ZIDCZTVDKDDDMW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 574486   

TargetTranscriptional enhancer factor TEF-1(Human)
Ikena Oncology

US Patent
LigandPNGBDBM574486(US11458149, Compound I-39)
Affinity DataEC50: >500nMAssay Description:TEAD inhibition can be assayed using Hippo Pathway TEAD Reporter MCF7 Cell Line (BPS Bioscience, Catalog #: 60618).More data for this Ligand-Target Pair
In DepthDetails
US Patent