BDBM573912 US11453697, Example 81::US11453697, Example 82::US11453697, Example 83::US11453697, Example 90::US11453697, Example 91::US11453697, Example 92

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)OC3[C@@H](COP(S)(=O)O[C@H]1C2O)O[C@H]([C@H]3F)n1cnc2c(N)ncnc12

InChI Key InChIKey=WXDFCKYYDRMTTP-UHFFFAOYSA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 573912   

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50: <1nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  21.5nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  3.70nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  1.70nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  15.8nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  114nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  3.10nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  14.6nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetStimulator of interferon genes protein [H232R](ZEBOV)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM573912(US11453697, Example 81 | US11453697, Example 90 | ...)
Affinity DataEC50:  4.40nMMore data for this Ligand-Target Pair
In DepthDetails
US Patent