BDBM573858 2-amino-9-[(5R,7R,8S,12aR,14R,15aS,16R)-14- (6-amino-9H-purin-9-yl)-16-fluoro-2,10- dihydroxy-2,10-dioxidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one::US11453697, Example 22
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)OC3C[C@@H](O[C@@H]3COP(O)(=O)O[C@H]1C2F)n1cnc2c(N)ncnc12
InChI Key InChIKey=FSQBZPVQQBPKOW-UHFFFAOYSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 573858
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 4.82E+3nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair