BDBM573849 2-amino-9- [(5R,7R,8R,12aR,14R,15R,15aS,16R)-14-(6- amino-9H-purin-9-yl)-2,10,15-trihydroxy-16- methoxy-2,10-dioxidooctahydro-12H-5,8- methanofuro[3,2-l][1,3,6,9,11,2,10] pentaoxadiphosphacyclotetradecin-7-yl]-1,9- dihydro-6H-purin-6-one::US11453697, Example 13
SMILES CO[C@@H]1[C@H]2COP(O)(=O)O[C@@H]3[C@@H](COP(O)(=O)O[C@H]1[C@@H](O2)n1cnc2c1nc(N)[nH]c2=O)O[C@H]([C@@H]3O)n1cnc2c(N)ncnc12
InChI Key InChIKey=HFCBZJVALDTJOW-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 573849
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 1.5nMAssay Description:The compounds were serially titrated by the Hamilton STARPlus CORE in a 96-well plate (Greiner, #651201) using a 1:3 ten-point dose response format. ...More data for this Ligand-Target Pair