BDBM572743 2-cyano-3-(3,5-dichloro-4-hydroxyphenyl)-N-(4-(naphthalen-2-yl)thiazol-2-yl)propanamide::US11453663, Preparative Example 143

SMILES Oc1c(Cl)cc(CC(C#N)C(=O)Nc2nc(cs2)-c2ccc3ccccc3c2)cc1Cl

InChI Key InChIKey=FCFOETBKMRFQCW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 572743   

TargetDouble-strand break repair protein MRE11(Human)
Masarykova Univerzita

US Patent
LigandPNGBDBM572743(US11453663, Preparative Example 143 | 2-cyano-3-(3...)
Affinity DataIC50: 6.00E+3nMAssay Description:The conditions of the assay are as follows:Microplate type: 1536 Well Black Round Bottom Polystyrene Not Treated (Corning cat no. 3936)Total reaction...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2022
Entry Details
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