BDBM570458 US11434233, Example 44b

SMILES C[C@@H]1COCCN1c1cc(N=[S@@](C)(=O)C2CC2)nc(n1)-n1c(C)nc2ccccc12

InChI Key InChIKey=IVXMCPRFCSMYPH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570458   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Human)
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM570458(US11434233, Example 44b)
Affinity DataIC50: 0.400nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
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US Patent