BDBM570449 N-[rac-(2R)-6-[-(2,2- difluoroethyl)piperazin-l-yl]- 2-(hydroxymethyl)-2-methyl- 3H-furo[2,3-b]pyridin-5- yl]pyrazolo[1,5-a]pyrimidine- 3-carboxamide::US11434250, Example 21

SMILES C[C@]1(CO)Cc2cc(NC(=O)c3cnn4cccnc34)c(nc2O1)N1CCN(CC(F)F)CC1

InChI Key InChIKey=PJYIDPMRAVTBCQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570449   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570449(N-[rac-(2R)-6-[-(2,2- difluoroethyl)piperazin-l-yl...)
Affinity DataKi:  13nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
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