BDBM570445 N-[rac-(3S)-7-[4-(2,2- difluoroethyl)piperazin-l-yl]- 3-hydroxy-3-methyl-2,4- dihydropyrano[2,3-b]pyridin- 6-yl]pyrazolo[1,5- a[pyrimidine-3-carboxamide::US11434250, Example 19

SMILES C[C@@]1(O)COc2nc(N3CCN(CC(F)F)CC3)c(NC(=O)c3cnn4cccnc34)cc2C1

InChI Key InChIKey=KZDUHQUGYVXKBH-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 570445   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570445(N-[rac-(3S)-7-[4-(2,2- difluoroethyl)piperazin-l-y...)
Affinity DataKi:  31nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent