BDBM570438 N-[(2S)-2-(1-Hydroxy-1-methyl-ethyl)-2-methyl-6-morpholino-3H-furo[2,3-b]pyridin-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide and N-[(2R)-2-(1-Hydroxy-1-methyl-ethyl)-2-methyl-6-morpholino-3H-furo[2,3-b]pyridin-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide::US11434250, Example 13::US11434250, Example 14

SMILES CC(C)(O)[C@]1(C)Cc2cc(NC(=O)c3cnn4cccnc34)c(nc2O1)N1CCOCC1

InChI Key InChIKey=BMCKJFJQDZNUAK-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 570438   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570438(N-[(2S)-2-(1-Hydroxy-1-methyl-ethyl)-2-methyl-6-mo...)
Affinity DataKi:  48nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570438(N-[(2S)-2-(1-Hydroxy-1-methyl-ethyl)-2-methyl-6-mo...)
Affinity DataKi:  91nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent