BDBM570432 (R) N-(6-(3-(Hydroxymethyl)morpholino)-2,2-dimethyl-2,3-dihydrofuro[2,3-b]pyridin-5-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide::US11434250, Example 7::US11434250, Example 8

SMILES CC1(C)Cc2cc(NC(=O)C(\C=N)=C3/NC=CC=N3)c(nc2O1)N1CCOC[C@@H]1CO

InChI Key InChIKey=UEJJEDCJPYTHJI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 570432   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570432(US11434250, Example 8 | (R) N-(6-(3-(Hydroxymethyl...)
Affinity DataKi:  820nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Genentech

US Patent
LigandPNGBDBM570432(US11434250, Example 8 | (R) N-(6-(3-(Hydroxymethyl...)
Affinity DataKi:  2.40E+3nMAssay Description:Kinase activities were assayed using the Transcreener-Fluorecescence polarization platform (BelBrook Labs, Madison, Wis., USA) that measures amounts ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2022
Entry Details
Go to US Patent