BDBM569190 (S)-(6-(6-(6-(amino(3-(hydroxymethyl)cyclobutyl)methyl)pyridin-2-yl)-1H-indazol-1-yl)pyridin-2-yl)methanol::US11427561, Compound 1::US11427561, Compound 3

SMILES N[C@@H](C1CC(CO)C1)c1cccc(n1)-c1ccc2cnn(-c3cccc(CO)n3)c2c1

InChI Key InChIKey=OYQBPBGVNDAZOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 569190   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569190(US11427561, Compound 3 | (S)-(6-(6-(6-(amino(3-(hy...)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM569190(US11427561, Compound 3 | (S)-(6-(6-(6-(amino(3-(hy...)
Affinity DataIC50: 100nMAssay Description:Biochemical Assay: The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2022
Entry Details
Go to US Patent