BDBM565488 (S)-4-(2-(2-((2,2'-dichloro- 3'-(5-(2-hydroxypropyl)-1- methyl-4,5,6,7-tetrahydro- 1H-imidazo[4,5-c]pyridine- 2-carboxamido)-[1,1'- biphenyl]-3-yl)carbamoyl)- 1-methyl-1,4,6,7-tetrahydro- 5H-imidazo[4,5-c]pyridin- 5- yl)ethyl)bicyclo[2.2.1]heptane- 1-carboxylic acid::US11414433, Example 14

SMILES CC[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3nc4CN(CCC56CCC(CC5)(C6)C(O)=O)CCc4n3C)c1Cl)n2C

InChI Key InChIKey=UZYPZMFCGDIGOQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 565488   

TargetProgrammed cell death 1 ligand/protein 1(Human)
Incyte

US Patent
LigandPNGBDBM565488(US11414433, Example 14 | (S)-4-(2-(2-((2,2'-dichlo...)
Affinity DataIC50: 5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
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Date in BDB:
10/30/2022
Entry Details
Go to US Patent