BDBM564528 US11414384, Example 142 Isomer 2
SMILES Cn1cc(cn1)-c1ccc2c(c[nH]c2c1)C(=O)[C@H](NCCc1ccc(cc1Cl)C(O)=O)c1ccccc1
InChI Key InChIKey=WAMYZVOQTGAIAL-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 564528
TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals
US Patent
Constellation Pharmaceuticals
US Patent
Affinity DataIC50: 81.6nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair