BDBM564274 US11414384, Example 98 Isomer 2
SMILES O=C([C@H](NCCc1ccc(cc1)C#N)c1ccccc1)c1c[nH]c2cc(ccc12)-c1cn[nH]c1
InChI Key InChIKey=BWEUTLKRALRPIQ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 564274
TargetHistone acetyltransferase p300 [1287-1666]/Histone acetyltransferase type B catalytic subunit(Human)
Constellation Pharmaceuticals
US Patent
Constellation Pharmaceuticals
US Patent
Affinity DataIC50: 58.3nMAssay Description:The p300 HAT domain (residues 1287-1666) was expressed and purified with an N-terminal His tag from Escherichia coli cells. The expressed protein was...More data for this Ligand-Target Pair