BDBM561990 BDBM50537617::BDBM561991::US11396496, Compound A8

SMILES COc1ccc(cc1)S(=O)(=O)N(C)c1cnc(N(CC(O)=O)S(=O)(=O)c2ccc(OC)cc2)c2ccccc12

InChI Key InChIKey=AUTGDVUDNHXSHF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 561990   

LigandPNGBDBM561990(BDBM561991 | BDBM50537617 | US11396496, Compound A...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Keap1-Nrf2 Interaction (unknown origin) by fluorescence anisotropyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/11/2021
Entry Details Article
PubMed
LigandPNGBDBM561990(BDBM561991 | BDBM50537617 | US11396496, Compound A...)
Affinity DataIC50: 1.10E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent

LigandPNGBDBM561990(BDBM561991 | BDBM50537617 | US11396496, Compound A...)
Affinity DataIC50: 1.23E+3nMAssay Description:The IC50 of the compounds for inhibiting the interaction of a fluorescent NRF2 peptide and the Kelch domain of KEAP1 was determined using fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
Go to US Patent