BDBM561416 3-(4-amino-2-((3-fluoropyridin-2-yl)methyl)-7-(pyridin-4-yl)-2H-[1,2,3]triazolo[4,5-c]pyridin-6-yl)benzonitrile::US11390624, Example 31::US20250041310, Compound 15

SMILES Nc1nc(-c2cccc(c2)C#N)c(-c2ccncc2)c2nn(Cc3ncccc3F)nc12

InChI Key InChIKey=UDTYMQWVZMEAGS-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 561416   

TargetAdenosine receptor A2b(Human)
Incyte

US Patent
LigandPNGBDBM561416(US11390624, Example 31 | 3-(4-amino-2-((3-fluoropy...)
Affinity DataEC50: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2B receptor (Perkin Elmer) were maintained in MEM culture medium with 10% FBS and 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561416(US11390624, Example 31 | 3-(4-amino-2-((3-fluoropy...)
Affinity DataKi: <10nMAssay Description:Stably transfected HEK-293 cells expressing the human adenosine A2A receptor (Perkin Elmer) are maintained in MEM culture medium with 10% FBS and 400...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Incyte

US Patent
LigandPNGBDBM561416(US11390624, Example 31 | 3-(4-amino-2-((3-fluoropy...)
In Depth
Date in BDB:
6/11/2025
Entry Details
Go to US Patent