BDBM561276 (6-(4-((4-(1H- pyrazol-4-yl) phenyl)amino)-6- methyl-6,7- dihydro-5H- pyrrolo[3,4- d]pyrimidin-2- yl)-1-methyl- 1H-indol-2- yl)(3,3- difluoroazetidin- 1-yl)methanone::US11390609, Compound TDI01954

SMILES CN1Cc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1ccc2cc(C(=O)N3CC(F)(F)C3)n(C)c2c1

InChI Key InChIKey=KZXOEKLKZYZKFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561276   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561276((6-(4-((4-(1H- pyrazol-4-yl) phenyl)amino)-6- meth...)
Affinity DataIC50: 14nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561276((6-(4-((4-(1H- pyrazol-4-yl) phenyl)amino)-6- meth...)
Affinity DataIC50: 1.00E+4nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent