BDBM561252 (3,3- difluoroazetidin- 1-yl)(6-(4-((3- methoxy-4- (1H-pyrazol-4- yl)phenyl)amino) pyrimidin-2-yl)- 1-methyl-1H- indol-2-yl) methanone::US11390609, Compound TDI01910

SMILES COc1cc(Nc2ccnc(n2)-c2ccc3cc(C(=O)N4CC(F)(F)C4)n(C)c3c2)ccc1-c1cn[nH]c1

InChI Key InChIKey=JZTUUKOTZKVQQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561252   

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561252((3,3- difluoroazetidin- 1-yl)(6-(4-((3- methoxy-4-...)
Affinity DataIC50: 6nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561252((3,3- difluoroazetidin- 1-yl)(6-(4-((3- methoxy-4-...)
Affinity DataIC50: 1.00E+4nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent