BDBM561132 1-(6-(4-((4- (1H-pyrazol-4- yl)phenyl)- amino)- pyrimidin-2- yl)benzo[b]- thiophene-2- carbonyl)- azetidine-3- carbonitrile::US11390609, Compound TDI01500

SMILES O=C(N1CC(C1)C#N)c1cc2ccc(cc2s1)-c1nccc(Nc2ccc(cc2)-c2cn[nH]c2)n1

InChI Key InChIKey=SDLUBIHQJXOYGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 561132   

TargetRho-associated protein kinase 1(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561132(1-(6-(4-((4- (1H-pyrazol-4- yl)phenyl)- amino)- py...)
Affinity DataIC50: 1.00E+4nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent

TargetRho-associated protein kinase 2(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM561132(1-(6-(4-((4- (1H-pyrazol-4- yl)phenyl)- amino)- py...)
Affinity DataIC50: 13nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/16/2022
Entry Details
Go to US Patent