BDBM558289 4-[3-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]phenyl]butanoic Acid::US11365192, Example 30-1

SMILES OC(=O)CCCc1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1

InChI Key InChIKey=HDZUBTKUDHSTGW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558289   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558289(US11365192, Example 30-1 | 4-[3-[[6-(1H-Pyrazol-5-...)
Affinity DataIC50: 1.40E+3nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558289(US11365192, Example 30-1 | 4-[3-[[6-(1H-Pyrazol-5-...)
Affinity DataIC50: 17nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent