BDBM558244 (2E)-3-[3-[[[6-(1H-Pyrazol-5-yl)pyridin-3-yl]oxy]methyl]phenyl]-2-propenoic Acid::US11365192, Example 22-1

SMILES OC(=O)\C=C\c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1

InChI Key InChIKey=GCLWOVMHRIJFCU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558244   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558244(US11365192, Example 22-1 | (2E)-3-[3-[[[6-(1H-Pyra...)
Affinity DataIC50: 140nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent

TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558244(US11365192, Example 22-1 | (2E)-3-[3-[[[6-(1H-Pyra...)
Affinity DataIC50: 15nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent