BDBM558230 6-[3-[[6-(1H-Pyrazol-5-yl)-3-pyridinyl]oxymethyl]phenyl]-2-pyridinecarboxylic Acid::US11365192, Example 18-1

SMILES OC(=O)c1cccc(n1)-c1cccc(COc2ccc(nc2)-c2ccn[nH]2)c1

InChI Key InChIKey=BRZSHHCZTXJLLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 558230   

TargetCytochrome P450 4F2(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558230(US11365192, Example 18-1 | 6-[3-[[6-(1H-Pyrazol-5-...)
Affinity DataIC50: 460nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
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TargetCytochrome P450 4A11(Human)
Taisho Pharmaceutical

US Patent
LigandPNGBDBM558230(US11365192, Example 18-1 | 6-[3-[[6-(1H-Pyrazol-5-...)
Affinity DataIC50: 13nMAssay Description:In the CYP4F2 inhibition test, the reaction solution containing each compound [final concentration of 50 mM, KPO4 (pH 7.4), 2.5 μM luciferine de...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2022
Entry Details
Go to US Patent